Alzheimer’s disease: 75 genetic risk factors discovered

The discovery of French scientists opens new perspectives in the treatment of the disease. © Adobe stock

French researchers have just identified 75 genes associated with Alzheimer’s disease. 42 of them are new. They open up new perspectives in screening and treatment.

A French discovery

It was French researchers from Inserm, the Institut Pasteur de Lille, the University Hospital of Lille and the University of Lille who were behind this discovery. They identified 42 new genetic factors in Alzheimer’s disease. This concerns 1 million 200,000 people in France. Their results have just been published in the journal Natural genetics.

Towards better Alzheimer’s screening?

This team of researchers detected 75 regions of the genome (called loci) associated with Alzheimer’s disease, including 42 new ones. Based on their results, the French scientists created a genetic risk score. The goal is to better assess people who could suffer from Alzheimer’s among people with cognitive disorders.

Evaluate the interest of the treatments

“This tool (…) could be very useful in setting up therapeutic trials to categorize participants according to their risk and better assess the benefit of drugs tested,” explained Jean-Charles Lambert, who led the study.

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